Breast cancer surgery


Intraoperative assessment of tumor resection margins in breast-conserving surgery using 18F-FDG Cerenkov luminescence imaging: a first-in-human feasibility study
Grootendorst MR, Cariati M, Pinder SE, Kothari A, Douek M, Kovacs T, Hamed H, Pawa A, Nimmo F, Owen J, Ramalingam V, Sethi S, Mistry S, Vyas K, Tuch DS, Britten A, Van Hemelrijck M, Cook GJ, Sibley-Allen C, Allen S, Purushotham A. J Nucl Med. 2017;58(6):891-898.

Outstanding Article Award from the Editors of JNM

Prostate cancer surgery

Intra-operative margin detection using Cerenkov Luminescence Imaging during radical prostatectomy – Initial results from the PRIME study
Michel C, Freeman A, Jameson C, Waddington W, Tuch D, Harboe M, Cathcart, P. 35th Congress of the European Society of Surgical Oncology, Vienna, 2015.


Performance evaluation of Cerenkov luminescence imaging: a comparison of 68Ga with 18F
J. olde Heuvel, B. J. de Wit-van der Veen, K. N. Vyas, D. S. Tuch, M. R. Grootendorst, M. P. M. Stokkel, C. H. Slump. EJNMMI Phys. 2019. 6: 17. 

Performance evaluation of the LightPath imaging system for intra-operative Cerenkov luminescence imaging
Ciarrocchi E, Vanhove C, Descamps B, De Lombaerde S,  Vandenberghe S, Belcari N. Physica Medica. 2018; 52:22–128.

Cerenkov luminescence imaging for image-guided cancer surgery
Grootendoorst MR, Cariati M, Kotari A, Tuch DS, Purushotham A.  Clinical and Translational Imaging. 2016; 4(5):353-366.